proteinubiquitin

由 M Sun 著作 · 2022 · 被引用 10 次 — Ubiquitination is a versatile post-translational modification (PTM), which regulates diverse fundamental features of protein substrates, ...

The ubiquitin protein itself consists of 76 amino acids and has a molecular mass of about 8.6 kDa. Key features include its C-terminal tail and the 7 lysine ...

由 KN Swatek 著作 · 2016 · 被引用 1651 次 — Protein ubiquitination is a dynamic multifaceted post-translational modification involved in nearly all aspects of eukaryotic biology.

由 DK Stringer 著作 · 2011 · 被引用 41 次 — Ubiquitination is a post-translational modification that generally directs proteins for degradation by the proteasome or by lysosomes.

由 A Ciechanover 著作 · 1998 · 被引用 553 次 — One of these, ubiquitin, an evolutionarily conserved protein of 76 residues, is activated in its C-terminal Gly to a high-energy thiol ester intermediate, a ...

由 J Callis 著作 · 2014 · 被引用 371 次 — The protein ubiquitin is a covalent modifier of proteins, including itself. The ubiquitin system encompasses the enzymes required for ...

由 HJ Guo 著作 · 2022 · 被引用 18 次 — One of the best understood functions of ubiquitination is protein degradation. This pathway targets proteins to the proteasome, which degrades ...

由 KN Swatek 著作 · 2016 · 被引用 1651 次 — Protein ubiquitination is a dynamic multifaceted post-translational modification involved in nearly all aspects of eukaryotic biology.

Ubiquitination is a small (76-amino acid) protein that is highly conserved and widely expressed in all eukaryotic cells. Ubiquitination involves one or more ...

Ubiquitinated protein aggregates provide a nuclear center for the formation of inclusion bodies, but there are several differences that distinguish these ...